KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRAS
All Species:
42.73
Human Site:
T144
Identified Species:
94
UniProt:
P01112
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01112
NP_001123914.1
189
21298
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
Chimpanzee
Pan troglodytes
XP_521702
189
21289
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
H
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540523
226
24555
T181
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61411
189
21330
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
Rat
Rattus norvegicus
P20171
189
21296
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08642
189
21347
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
Frog
Xenopus laevis
Q91806
189
21364
T144
Y
G
I
P
F
I
E
T
S
A
K
T
R
Q
G
Zebra Danio
Brachydanio rerio
P79737
188
21321
T143
Y
G
I
E
F
V
E
T
S
A
K
T
R
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08646
189
21575
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
M
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P22981
184
20964
T144
Y
G
I
P
N
V
D
T
S
A
K
T
R
M
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
T150
F
G
T
K
Y
I
E
T
S
A
K
T
Q
H
N
Conservation
Percent
Protein Identity:
100
99.4
N.A.
81.8
N.A.
99.4
99.4
N.A.
N.A.
97.8
84.1
83
N.A.
77.2
N.A.
74.5
N.A.
Protein Similarity:
100
99.4
N.A.
83.1
N.A.
99.4
99.4
N.A.
N.A.
99.4
93.1
91.5
N.A.
85.1
N.A.
85.1
N.A.
P-Site Identity:
100
93.3
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
80
N.A.
93.3
N.A.
73.3
N.A.
P-Site Similarity:
100
93.3
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
59.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
69
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
91
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
91
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% H
% Ile:
0
0
91
0
0
82
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
100
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
64
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
100
0
0
0
100
0
0
0
% T
% Val:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
91
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _